Inhaled sodium cromoglycate in children with asthma
نویسندگان
چکیده
منابع مشابه
Sodium cromoglycate in nocturnal asthma.
To investigate whether mast cell degranulation was important in producing nocturnal asthma, the effect of a single high dose of nebulised sodium cromoglycate on overnight bronchoconstriction, oxygen saturation, and breathing patterns in eight patients with nocturnal wheeze was examined. The study took the form of a double blind placebo controlled crossover comparison. Treatment with cromoglycat...
متن کاملSodium cromoglycate in childhood asthma.
The review of placebo controlled trials of sodium cromoglycate (SCG) in childhood asthma by Tasche et al concludes that “there is insuYcient evidence that SCG has a beneficial eVect as maintenance treatment in children with asthma”. We do not believe this conclusion is justified. The principal criteria for assessing the eYcacy of inhaled SCG are the mean diVerences in the eVect on the symptoms ...
متن کاملLETTERS TO THE EDITOR Inhaled sodium cromoglycate
The systematic review and meta-analysis performed by Tasche and colleagues appears to have been carried out with commendable thoroughness. The results seem clear cut: sodium cromoglycate is ineVective as maintenance therapy in children with asthma. However, their conclusions are not objective but depend in the final analysis on their multivariate regression model. Perhaps this is where the most...
متن کاملRandomised placebo-controlled trial of inhaled sodium cromoglycate in 1-4-year-old children with moderate asthma.
BACKGROUND Inhalation therapy with sodium cromoglycate is recommended as the first-line prophylactic treatment for moderate asthma in children. The availability of spacer devices with face-masks has extended the applicability of metered-dose inhalers to younger children. We studied the feasibility and effects of this therapy compared with placebo in children aged 1-4 years. METHODS 218 childr...
متن کاملLETTERS TO THE EDITOR Inhaled sodium cromoglycate
The systematic review and meta-analysis performed by Tasche and colleagues appears to have been carried out with commendable thoroughness. The results seem clear cut: sodium cromoglycate is ineVective as maintenance therapy in children with asthma. However, their conclusions are not objective but depend in the final analysis on their multivariate regression model. Perhaps this is where the most...
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ژورنال
عنوان ژورنال: Thorax
سال: 2002
ISSN: 0040-6376
DOI: 10.1136/thorax.57.8.751-b